High Tech: The Wired World of Cannabis
From science to business, a look back at some of our best 4/20-adjacent coverage.
Photo: ANDREW HARRER/BLOOMBERG/GETTY IMAGES01Jeff Sessions' War on Medical Marijuana Gets Public Health All Wrong
The current attorney general has a well-documented distaste for weed—but his personal feelings disregard a huge amount of scientific and observational data.
Photo: CODY RASMUSSEN/GETTY IMAGES02Scientists Map the Receptor That Makes Weed Work
After discovering exactly how humans’ CB1 receptors operate, a team of chemists hope to bypass THC entirely, creating finely-tuned molecules that will trigger the receptors to send pain-relief signals to the body—without things like irritability, anxiety, or federal prosecution.
Photo: GARY MORRISON/GETTY IMAGES03The Future of Weed Science Is a Van in Colorado
There’s no shortage of reasons to study cannabis—but federal law prohibits using anything but specially grown strains meant for research. There’s just one problem: lab weed is weak. The solution? A mobile lab that can accommodate real-life users and their real-life stash.
Photo: GETTY IMAGES04Why No Gadget Can Prove How Stoned You Are
A cannabis high can be rather unpredictable, depending on strain, THC levels, and the interaction between hundreds of other these compounds. But as medical and recreational marijuana use spreads across the United States, how can law enforcement tell if someone they’ve pulled over is too high to be driving?
Photo: DOSIST05Why It's So Hard to Dose Weed
Your reaction to cannabis depends as much on your physiology and state of mind as it does on the plant. But science is always learning about how marijuana works on the human body—companies are figuring out ways to help you dose more consistently.
Photo: BEATE SONNENBERG06The Plan to Save California's Legendary Weed From 'Big Cannabis'
The recent legalization of recreational use in California may seem like a bonanza for marijuana farmers—but the situation is less peachy for small operators, who have to cope with a sprawling new bureaucracy governing the cultivation and distribution of marijuana. One company thinks it has an answer.
Sessions' War on Medical Weed Gets Public Health All Wrong
Using the opioid crisis to justify cracking down on medical marijuana isn’t just disingenuous, it’s irresponsible. Because weed is actually pretty great at managing chronic pain.
Megan Molteni
Scientists Map the Receptor That Makes Weed Work
A better understanding of the on-switch for cannabis could help researchers design THC-like molecules without the side effects.
Nick Stockton
The Future of Weed Science Is a Van in Colorado
"The idea is: If we can’t bring real-world cannabis into the lab, let’s bring the lab to the people.”
Robbie Gonzalez
Why No Gadget Can Prove How Stoned You Are
Marijuana is such a confounding drug that scientists and law enforcement are struggling to create an objective standard for marijuana intoxication.
Matt Simon
Why It's So Hard to Dose Weed
Too much weed = a very bad time. But companies making cannabis devices are figuring out ways to tackle the dosing problem.
Matt Simon
The Plan to Save California's Weed From 'Big Cannabis'
Inside the sprawling new facility that wants to help small cannabis farmers survive the invasion of Big Cannabis.
Matt Simon
Anthropic Says It Will Revolutionize Biology—Some Day
In breathless press releases and posts, the company has touted its models’ ability to deliver scientific breakthroughs. But its IPO filing taps the brakes on just how fast its AI will lead to big discoveries.
Emily Mullin
How Elizabeth Holmes Tricked WIRED—and Everyone Else
WIRED was the first magazine to cover Theranos and its enticing billionaire founder. There were warning signs even then.
Adam Rogers
Inside the Exclusive Nathan Fielder Interview
This week on Uncanny Valley, we go behind the scenes of our Nathan Fielder cover story, unpack tech billionaires’ generous promises, and discuss the suspicious letters sent to US election offices.
Brian Barrett
The Story of Billy Evans and ‘Theranos 2.0’
Elizabeth Holmes’ husband is a major figure in Nathan Fielder’s new documentary. But who is Billy Evans—and is he really working on a second blood-testing company?
Christopher Hooks
OpenAI Invests in Startup That Uses Brain Implants to Detect Cancer
It’s the latest in a growing wave of bets that AI companies are making on brain data.
Emily Mullin
9 WIRED-Approved Gifts for the Techie in Your Life
Don’t buy a loved one something you wouldn’t want for yourself. These are the must-haves that tech enthusiasts have on their wish lists this year.
Luke Larsen